Monday, September 3, 2012

An Overlooked Conditioning Technique May benefit Asthmatic Sufferers

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Professional athletes, Olympic athletes and those serious-minded athletes who seek to improve their operation often train at mountain resorts where thin air, less oxygen, demands strenuous training to attain desired results. Indeed, high altitude visits has established its prominence in widespread conditioning and endurance but also has applications for asthmatic patients and those individuals with illnesses having an underlying allergic component as well as disorders unrelated to allergy. While trips to high altitude resorts for extended periods may be impractical for most people, simulated exposures to the low pressure of high altitude in an altitude accommodation merits serious consideration and the availability of these chambers is imaginable to growth over the next decade.

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A brief impart of the history of simulated high altitude as a therapy and for conditioning is in order. In the early 1950s the scientist Solco W. Tromp, Ph.D., a Dutch geologist by training and co-founder of the prestigious International community of Biometeorology (biometeorology.org - 1956), made a appealing observation. He noted that children with asthma were relieved of their symptoms whenever they skied downhill but not cross country. As a scientist he wondered if this straightforward consideration could be verified under controlled clinical conditions. For this purpose he retrofitted altitude chambers imported from Germany and in cooperation with the medical school and hospital in Leiden, The Netherlands conducted study that lasted more than 30 years and is today documented with 41 papers by Tromp in the Medline index of the PubMed archives of the National Library of Medicine. A link with reference to Tromp's basic protocol is provided below. This does not take into inventory the numerous out of print books and texts Tromp authored on the pioneering science of Biometeorology. His prolific contributions to the literature of health and science are best appreciated by entering his name, as S.W. Tromp, in amazon.com (books), used.addall.com and the Google hunt engine. Nevertheless, as with many non-medical, non-surgical therapeutic modalities Tromp's work went largely ignored by preparation medicine which advocated then as now pharmacological-researched therapy.

Although commonly known as altitude chambers they are more appropriately called hypobaric (low pressure) chambers. Hypobaric chambers should not be confused with the more widely utilized hyperbaric (high pressure) chambers. When compared, hypobaric exposure simulates ascending in an airplane while hyperbaric exposure simulates descending in a submarine requiring oxygen administration and both chambers have similar yet distinct physiologic benefits for users. The late F. Joseph Whelan, M.D., a clinician connected with the hypobaric technology, coined the term "cellular calisthenics" to impart the effects of controlled pressure exposures on cells. As a result of the general aging process, disease or injury some cellular workings diminish while adjacent cells function sufficiently to retain life. When all cells are simultaneously stressed by prescribed pressure and/or climatic characteristic changes they respond or improve their roles by re-establishing general expansion-contraction of their membranous cell walls to initiate and improve metabolic functions that consist of respiration, circulation, digestion, assimilation, reproduction, urination etc. This process is view base to both the hypobaric and hyperbaric accommodation sojourns and since cellular improvement results from prescribed pressure changes the conditioning and therapeutic applications are theoretically far reaching.

This writer has no contact with hyperbaric chambers or hyperbaric oxygenation protocols and nothing written additional should be construed to pertain to its uses.

Whelan's principles of "cellular calisthenics," in collaboration with this writer, takes on its greatest significance with the fact that the human body is composed of 75 trillion cells ranging from the simplest epithelial cells to extremely specialized organ cells. While each cell performs its metabolic functions the cell's most leading process is the output of adenosine triphosphate (Atp) that immediately breaks down to adenosine diphosphate (Adp) to issue power which is defined as "The ability to do work." As cells improve their function "to do work" the realization becomes apparent that cells collectively consist of tissues which make up organs that in turn consist of systems and ultimately systems that function to capacity precisely improve their "interface of interdependence" for maximum efficiency. It follows that immunologic function improves as does the administration of stressful demands. Whelan additional believed that with needful objective improvement (based on the PubMed archived Tromp protocol expressed in the paper, "Influence of weather and atmosphere on asthma and bronchitis," http://www.ncbi.nlm.nih.gov/pubmed/5702098 ) a trial of antibiotic therapy would sustain the metabolic function of urination (bacteria reduction) and Applied Kinesiology (Ak) testing and techniques could accurately monitor the efficacy of this trial.

The effects on human physiology at high altitude are unique since healthy athletes and individuals with varying conditions benefit from its exposure whether simulated or natural. As an example, the natural parallel to hypobaric usage would occur on the Hawaiian island of Maui where an personel would start at sea level then drive up the inactive volcano Mt. Haleakala (a tourist attraction), remain at its summit of 10,000 feet (3048 meters) for one full hour then drive back down to sea level. This is a very safe procedure that has no harmful effects for most tourists who trip this journey daily. The first observable physiological turn occurs pre and post sojourn measurements of urinary pH with a post shift to the alkaline right. personel diets can occasionally influence this finding.

In high altitude physiology, whether simulated or natural, oxygen availability decreases. This decrease in oxygen reflexively stimulates the kidneys to growth their general output of the human growth hormone erythropoeitin, Epo. Artificial Epo is an invaluable therapy for the dialysis patient but Epo has been unscrupulously administered by prescribing physicians in what is now commonly known as "blood doping" to maximize athletic performance.

Overall conditioning and endurance improve when raised Epo levels migrate to the long bones (arms and legs) to stimulate additional output of red blood cells (Rbcs) from bone marrow. These Rbcs then circulate to the lungs to improve pulmonary function thus resulting in chest wall expansion and an increased vehicle of Rbcs throughout the body. This phenomenon has such therapeutic and conditioning implications that it is nothing short of being termed a "biological classic" that has yet to be fully realized and appreciated. It is grand that Epo output is increased naturally up to 50 times with accommodation usage and more than a thousand times by its Artificial administration.

The major difference in the middle of visits to a high altitude resort and hypobaric accommodation exposures is that with the former after a short period of time the body only acclimates to the atmospheric altitude pressure turn while with accommodation exposures "cellular calisthenics" occurs development it analogous to a regimented practice routine. By a series of innovative experiments Tromp proved that these repeated exposures resulted in needful corrections and what appeared to be cures in some patients.

During his lifetime of study Tromp done that hypobaric exposures became optimally therapeutic with a prescribed pressure simulating 8200 feet (2500 meters) for one full hour period three or four times a week until a minimum of 50 sojourns to an optimal 100 sojourns was accomplished. For those rare patients unable to tolerate this pressure or where otherwise contraindicated Tromp realized that pressure simulating 5000 feet (1524 meters) provided a minimal therapeutic threshold. Pressure below 5000 feet was of no conditioning or therapeutic value while that above 8200 feet prepared mountain climbers and personnel complex in aerospace programs to tolerate the significantly lower pressure of higher altitudes.

The noted scientist and philanthropist Mr. Shelley Krasnow, founder and president of Georator Corporation, is singlehandedly credited for importing this technology to the United States. His second medical paper indexed in PubMed entitled, "Geographic patterns of large intestine and rectal malignancy mortality in Virginia," ( http://www.ncbi.nlm.nih.gov/pubmed/5528099 ) was preceded by his equally appealing prognosis in the study paper, "Physiological chilling as a possible factor in mortality from neoplasia" that paralleled the work of Tromp and resulted in a close personal friendship that lasted until Tromp's passing. This writer is honored and privileged to have worked intimately with Shelley Krasnow from 1982 until his untimely death in 1989 and still maintains the protocols established by Tromp.

As a final view the cases of my first two patients who completed and precisely exceeded the accommodation protocol is offered to construe the diversity of patients/clients who can be helped with this conditioning procedure. The first complex a divorced 28 year old female without children whose chief complaint was progressive unilateral upper and lower extremity weakness. Objective exam confirmed her complaint which failed to respond to conservative chiropractic management. A neurological consult was ordered with a suspected impression of possible demyelenating disease as the cause for her symptoms. As neither Cat nor Mri scans were effortlessly available (1982) she elected to decline any invasive confirmatory procedure instead opting to try the accommodation conditioning protocol. As the sessions increased in estimate her symptoms very moderately improved which inspired her to seek additional complementary therapies. These included acupuncture, Applied Kinesiology (Ak), homeopathy and lifestyle changes that when integrated continued to improve her condition. Today she is fully functional, gainfully employed, but on chance experiences minimal to moderate discomforts.

In the second case a young man who served in the navy as an aircraft carrier jet mechanic continued this work into civilian life. It was while working for a major airline in Chicago years later that he and a colleague serviced an aircraft on the tarmac at night in subzero weather. Both men collapsed on the job and were rushed to the Er for assessment where a prognosis of sudden onset of asthma was established. They were treated accordingly. When this personel became my patient for non-related musculoskeletal complaints I suggested a trial in the accommodation which he effortlessly agreed to pursue. Within a short period subjective and objective pulmonary improvements became evident. He had always maintained consultation with his pulmonologist until he at last relocated to Hawaii where I'm sure he's a quarterly and frequent visitor to Mt. Haleakala.

Not unlike my predecessors I have often tried and failed to generate interest within the medical arts community to this straightforward technology. But it seems that well meaning docs are more interested in maintaining their own specialized turf than referring patients to trial a new but safe procedure. And so I'm left to fantasize if victims of such catastrophes as Gulf War Syndrome, Legionnaires' Disease or respiratory disorders afflicting first responders to the 9/11 horrors could have been saved by a technology that succeeds with clinically verifiable outcomes. I presuppose expert athletes in their quest to legally attain the competitive edge will be first on line to embrace hypobaric accommodation conditioning.

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